<p>It depends on your goal:</p><p></p><ul><li>If you want more sustain and profit, meaning you want to use less pots, therefore take less damage, then you should attack the one with less HP. It will die first, and then you will have 1 less creature attacking you, meaning you won't have to heal as much.</li><li>If much.</li></ul><div></div><ul><li>If your goal is maximize your experience and you have 8 creatures on you, + creatures around, then you should also attack the one with less HP, this way it will die faster and be replaced by one of the creatures roaming around. Therefore, that creature will start to take damage faster, increasing your exp, slightly.</li><li>If slightly.</li></ul><div></div><ul><li>If your goal is maximize your experience, but you don't have extra creatures roaming around, then you should focus on the creature with higher HP, meaning the odds of you having to stay with just 1 creature at the end are lower, everything will die at the same time and you can move on to next pull.</li></ul>