It might have a high impact, impact but will always depend of which hunt are u you doing.
For example, Rp hunting Ghastly Dragons with bow and crossbow. This case I prefer crossbow cuz e because you can make spectral bolts every 10minutes, so 10minutes. I use 100infernal then 100spectral. 100 spectral. This hunt to kill one by one is better than lure, cuz u lure because you can't lure much o of them (low resp, and u respawn, and you probably die). U You have to analyse too to about imbuements slots, some hunt u need more imbuements than others.
So, changing weapons have a high impact but it will depends wich hunt are u doing.which hunt are u doing.