<p>I assume the only items that can't be used in the <a rel="nofollow" href="https://tibia.fandom.com/wiki/Tibiadrome">Tibiadrome</a> are the same that could not be used on <a rel="nofollow" href="https://tibia.fandom.com/wiki/Monster_Arena">monster arenas</a> (and can't still be used on <a rel="nofollow" href="https://tibia.fandom.com/wiki/Duelling_Arena">PvP arenas</a>), i.e items that teleport you when used:</p><ul><li><a rel="nofollow" href="https://tibia.fandom.com/wiki/Boots_of_Homecoming">Boots of Homecoming</a></li><li>The Store-bought <a rel="nofollow" href="https://tibia.fandom.com/wiki/Temple_Teleport_Scroll">Temple Teleport Scroll</a></li><li>The <a rel="nofollow" href="https://tibia.fandom.com/wiki/Daily_Reward_System">Weekly</a> free temporary temple teleport scroll</li><li><a rel="nofollow" href="https://tibia.fandom.com/wiki/The_Supreme_Cube">The Supreme Cube</a></li></ul><p><a Cube</a></li></ul><p>Additionally, you cannot attempt to make a <a rel="nofollow" href="https://tibia.fandom.com/wiki/Ring_of_Ending">Ring of Ending</a> by using a <a rel="nofollow" href="https://tibia.fandom.com/wiki/String_of_Mending">String of Mending</a> on a <a rel="nofollow" href="https://tibia.fandom.com/wiki/Broken_Ring_of_Ending">Broken Ring of Ending</a> there (thanks <a rel="nofollow" href="https://www.tibiaqa.com/user/shawtay">Shawtay</a> for testing this).</p><p><a rel="nofollow" href="https://tibia.fandom.com/wiki/Cupcakes">Cupcakes</a>, <a rel="nofollow" href="https://tibia.fandom.com/wiki/Hot_Cuisine_Quest/Spoiler#Reward_2">Hot Cuisine's dishes</a> and <a rel="nofollow" href="https://tibia.fandom.com/wiki/Hireling#Hireling_Cook">Hireling dishes</a> can be used and, unlike runes, ammunitions and potions, they will be consumed when used.</p>