There If you mean a route depends on which bosses - it strictly depends on probability of bosses' appearance, so the there is no good answer for that, because each day the probabilyty of bosses spawn is diferent, answer.
If you mean way to hunt them - then it's more difficult. I used to focus on bosses with profitable and rare loot, count the probability of it's appearance to avoid wasting time on bosses without any chance to appear. I'm checking that day.
it as often as possible (but not more often than 20 mins) and I'm not camping it to not block floor resets... and it's all I guess.
It also depends on what you expect - only profit or maybe some RPG, chllenge or you are a collector.
Different kind of bosses requires different tactics. This question is simply a little bit too broad.