Hive Bosses are usually surrounded with other mobs such us Waspoid's, Insectoids Worker's, Crawlers, Spitters and :
Hive Overseer (summoning 2 Spidris Elite), Kollos,
Spidris Elite & Spidris
Level recommended: 300+
Weapon's Recommendations: Winterblade (from the 200 lvl)/ Gnome Sword (from the 250 lvl), Cobra Axe ( from the 220 lvl)/ Falcon Battleaxe (from the 300 lvl), Resizer( from the 230 lvl)/ Falcon Mace (from 300 lvl)
Tactic 1- Take it slow.
Move slowly and kill mobs on the way to the bosses to make sure they will not follow you and block you. Corner Hive Overseer (try to separate them and deal individually) and kill him as fast as possible. Once the place is cleared, focus on the Boss. note: Mew will be behaving like Overseerer and will attack you from distance. You will have to corner him.
Tactic 2. Run Fast.
Run Quickly next to the wall (not many mobs is respawning next to the wall). Help yourself with Energy Bomb Rune's and Energy Wall Rune's. It is recommended to use them to have an escape route in case mobs are lured in large amount. You will still have to kill mobs around the bosses.