I'll post an partial answer, since I don't have an ED on this level I cannot test it to give you details on xp/h and profit, but I can say some spots that I personally saw friends hunting on those spots.
1) Deeper Iksupan (probably the best ratio xp/profit but the most dangerous place) --> Protection against death, energy and physical (not necessary in this order, need to test what will give you the most impact)
2) Port hope lost souls (another hunt with a good xp ratio but poor profit) --> Protection against life drain and death, beware on areas with lower space to run
3) Falcon bastion (probably the second best ratio xp/profit but similar dangerous of deeper iksupan) --> Protection against energy, physical and holy, prismatic ring and void boots will probably be needed here. Beware of traps
4) Werelion (not the best xp but a good profit hunt) --> Protection against fire, holy and physical
5) Summer courts (a good hunt to profit and xp but a dangerous place, mainly on +1 and +2) --> Protection against fire and physical, a little against death because of the arachnophobicas