There aren't many items that give us life drain protection.
The best protection you can have is 57,75% by using:
People tend to use Garlic Necklace (20% res) due to its price
Here is a list of all the items you can use to protect yourself against life drain, however, there are no armors, legs, helmets, shields or weapons protecting against life drain.
Question Revival II contestJanuary 06, 2021
Third Anniversary InfographicDecember 28, 2020
Edit notifications for users who downvoted the postNovember 02, 2020
Looking for a community managerJune 09, 2019